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Myostatin Deficiency

Description

Often referred to as the “bully gene”. Myostatin is a growth factor responsible for controlling the development of muscle fibres. When the myostatin-producing gene is unable to function properly, excess muscling develops. Inheriting two copies of the mutation (one from each parent) results in a whippet with almost twice the amount of normal muscling. Although whippets with one copy of the mutation appear normal but may be more muscular than whippets not carrying the mutation, there is no real way to tell whether a whippet carries the gene just by its appearance. Double-muscled whippets exist in several unrelated lines in North America and Europe and, although this problem is now small, it appears to be growing.

Recommended Breeding

Diseases

Myostatin Deficiency

$ 50.00

1

Associated Breed(s):

Click here to view Associated Breeds

Labels:

Category:

Musculoskeletal - Associated with muscles, bones and associated structures

Severity:

Low. This disease generally causes mild signs of disease, or can be quite easily treated/managed.

Gene:

Myostatin (MSTN) on Chromosome 37

Variant Detected:

Nucleotide Deletion c.939-940del p.Cys313STOP

Mode of Inheritance:

Autosomal Recessive

OMIA Reference:

Click to View Full OMIA Reference