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Leigh-Like Subacute Necrotising Encephalopathy

Description

Leigh-Like Subacute Necrotising Encephalopathy affects dogs and is a neurodegenerative disorder. This disease is characterised by symmetrical, bilateral and necrotic lesions in the basal ganglia and brainstem. 
It is a mitochondrial disease caused by defects from the respiratory chain and leads to impaired energy production. 
Symptoms include seizures, dysphagia (difficulties swallowing), paresis (weakness), visual deficits, neurological deficits, behavioural changes and ataxia (incoordination). 
This disease is usually fatal.

Recommended Breeding

Diseases

Leigh-Like Subacute Necrotising Encephalopathy

$ 50.00

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Associated Breed(s):

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Labels:

Category:

Nervous system / Neurologic - Associated with the brain, spinal cord and nerves

Severity:

Severe. This disease has a high impact on affected animals, either with severe clinical signs causing significant suffering, or carrying a rapidly fatal course.

Gene:

SLC19A3

Variant Detected:

Mode of Inheritance:

Autosomal Recessive

OMIA Reference:

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